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Experts Establish Thresholds for Amino Acids

Representatives from the Council for Responsible Nutrition (CRN), Washington, D.C., recently authored risk assessments establishing safe upper intake levels for the amino acids taurine (Tau), glutamine (Gln) and arginine (Arg). The authors concluded that the absence of adverse effects is strong for Tau at up to a dose of 3 grams per day; for Gln at up to 14 grams per day; and for Arg at up to 20 grams per day. The paper, published in the April issue of the peer-reviewed journal Regulatory Toxicology and Pharmacology, was co-authored by CRN scientists John Hathcock, PhD, and Andrew Shao, PhD. They reviewed published randomized, controlled clinical trials conducted in humans involving these three amino acids and relied on uncontrolled trials and animal data as supportive information.

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